Biological Functions in Royal Jelly

Commentary - Journal of Apitherapy (2022)

Biological Functions in Royal Jelly

Filippo Fratini*
Department of Veterinary Sciences, University of Pisa, Italy
*Corresponding Author:

Filippo Fratini, Department of Veterinary Sciences, University of Pisa, Pisa, Italy, Email:

Received: 19-Jan-2022, Manuscript No. JAPITHERPAY-22-52128; Editor assigned: 21-Jan-2022, Pre QC No. JAPITHERPAY-22-52128 (PQ); Reviewed: 04-Feb-2022, QC No. JAPITHERPAY-22-52128; Revised: 09-Feb-2022, Manuscript No. JAPITHERPAY-22-52128 (R); Published: 16-Feb-2022


Due to its vast traditional applications and potential future usefulness in medicine, royal jelly and its protein and lipid components have recently been exposed to many investigations into its antibacterial properties. Royal jelly is a bee product that is widely utilized in cosmetics, medicine and other industries. Royal jelly can not only govern the physiological function of bee populations, but it can also have a biological role in a variety of disorders. This paper reviews the main active ingredients in the functional food royal jelly, such as major royal jelly protein, fatty acids, phenols, flavonoids and others, and summarizes the active role of royal jelly in the maintenance of human health, including immunity, lifespan, memory, digestive system, blood glucose, obesity, antibacterial, and anti-cancer effects, among which memory regulation can be used in the treatment of Alzheimer’s disease. As larval sustenance, honey bees provide glandular secretions in the form of royal jelly to developing queens. Chemicals and dietary circumstances can have an impact on queen development and, as a result, colony fitness. Royal jelly stays pesticide-free following colony-level exposure, according to previous study and chemical residues are buffered by nurse bees. Pesticides, on the other hand, can affect the quality and quantity of royal jelly produced by nurse bees. In the emerging evolutionary ecological genetics, understanding the molecular processes that modulate organism variances and selection signatures to induce adaptive evolutionary changes is a must. Through whole-genome sequencing of DNA from eight honeybee populations, we were able to identify the gene locus linked to royal jelly production.The goal of this research is to find out how different honeybee stocks produce distinct volatile components in royal jelly. Headspace- solid phase micro-extraction was used to extract volatile components from three RJ samples from high and low royal jelly production honeybee stocks, which were then evaluated using gas chromatography- mass spectrometry. The fact that honeybee stock selected for increasing royal jelly yields has shaped a distinct volatile component profile compared to the unselected Italian bees is suggested by principal component analysis and hierarchical clustering analysis of the volatile components. this product of the hypopharyngeal glands of worker bees has received attention because of its necessity for the development of queen honeybees as well as claims of benefits on human health. Despite prior glycomic and glycoproteomic studies, none of the previously identified glycan structures appear to have the potential to trigger specific biological processes. The biological activities of royal jelly have been documented to include vasorelaxation and blood pressure reduction. Although functional meals are beneficial to one’s health, little research has been done on the effects of royal jelly on the cardiovascular system in healthy people. As a result, we looked into the mechanisms behind royal jelly vasorelaxation effects in healthy control rats to see if the peripheral circulation was improved. Crude Royal Jelly, Royalisin, 10-hydroxy-2-decenoic acid, Jelleines, and Major Royal Jelly Proteins have been shown to exhibit antimicrobial activity against a variety of bacteria. All of these beehive products have antibacterial properties, indicating that they might be used as natural additives in a variety of industries. Royal Jelly and its derivatives are particularly effective against gram-positive bacteria.

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