Royal Jelly: Beneficial Effects in Human Health

Commentary - Journal of Apitherapy (2022)

Royal Jelly: Beneficial Effects in Human Health

Nazan Kavas*
Department of Food Technology, Ege University, Izmir, Turkey
*Corresponding Author:

Nazan Kavas, Department of Food Technology, Ege University, Izmir, Turkey, Email:

Received: 15-Apr-2022, Manuscript No. JAPITHERPY-22- 65239; Editor assigned: 18-Apr-2022, Pre QC No. JAPITHERPY-22- 65239 (PQ); Reviewed: 03-May-2022, QC No. JAPITHERPY-22- 65239; Revised: 09-May-2022, Manuscript No. JAPITHERPY-22- 65239 (R); Published: 16-May-2022


Royal jelly is a honey bee secretion that is used to feed the larvae and adult queens of honey bee colonies. It is produced by nursing bees’ hypo pharyngeal glands and fed to all larvae in the colony, independent of sex or caste. The workers build unique queen cells during the process of making new queens. Royal jelly is supplied to the larvae in these cells in large quantities. The development of queen morphology, including fully developed ovaries required for egg laying, is triggered by this type of nutrition. Apitherapy is a term for the use of royal jelly in alternative medicine. Although it is frequently advertised as a human dietary supplement, the European Food Safety Authority has determined that current research does not support the claim that royal jelly consumption provides health advantages to humans. The Food and Drug Administration in the United States has taken legal action against corporations that have advertised royal jelly products with unsubstantiated health claims. In China, migratory beekeeping of a high royal jelly -producing honeybee strain produces over 90% of worldwide royal jelly, a functional food with different health advantages. We used metabolomics and proteomics studies, as well as royal jelly antioxidant activity, to look at how the quality of royal jelly produced by migratory royal jelly changed over time. The metabolic and proteomic profiles of RJs were shown to alter with floral phases in general. Honeybees have strong pollination ability and play a key role in raising food yields and plant genetic diversity, resulting in significant economic benefits for humans. However, a variety of biological and abiotic factors, such as the effects of fungi, bacteria, viruses, parasites, and especially agrochemicals, have an impact on honeybee survival. Honeybees have been observed to be killed or injured by glyphosate, a broad-spectrum herbicide used largely for weed control in agriculture. Royal jelly and honeycomb are widely consumed, while royal jelly-related anaphylaxis is uncommon. In China, no cases of anaphylaxis have been reported after consuming royal jelly. Its honeycomb cross-reactivity is currently unknown. Royal jelly regulates the nutritional development of honeybee castes royal jelly. Major royal jelly protein 1, the most abundant glycoprotein among soluble royal jelly proteins, is important for honeybee feeding and larval development, as well as having a wide range of pharmacological effects in humans. In carbendazim- treated bees, important royal jelly proteins, a vital multifunctional protein family with an indispensable role in colony growth, were dramatically reduced. This was confirmed in nurse bees’ heads and hypo pharyngeal glands. Furthermore, carbendazim therapy likely slowed visual and olfactory loss, immunological functions, muscular activity, social behaviour, neural and brain development, protein synthesis and modification, and metabolism-related proteins. These findings imply that carbendazim is an environmental risk factor that weakens bee colonies, possibly as a result of lower expression of important royal jelly proteins, which could be potential causes of colony collapse disorder. Royal jelly is a nutrient-dense meal with health-promoting properties. The functional chemicals, on the other hand, are still unknown. We used the Osboren method to fractionate the royal jelly proteins of Xinjing black bees.

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